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Wątek: NATURALNE sposoby optymalizacji CIAŁA i DUSZY.

  1. #1081
    Sztywny Pal Azji Awatar Stud
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    Witam Cie serdecznie, dobrze trafiłeś

    na początek podam taki zabawny obrazek do przemyślenia



    mniej zabawnie będzie jak powiem, że tak to wygląda

    czas coś zmienić, chyba, że interesują Cię chory wieku podeszłego w jego kwiecie.

    Wyjdę na hipokrytę, bo ja doskonale wiem co i jak, mimo wszystko, robię, jak robię.

    Ale chętnie poczytam jeszcze jakiś Twój wywód.

  2. #1082
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    Ps. 30 za rok, jeszcze ciągnę.
    Ostatnio edytowane przez Stud ; 29-03-20 o 21:18

  3. #1083
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    Wyjdę na hipokrytę, bo ja doskonale wiem co i jak, mimo wszystko, robię, jak robię.
    tzn, że nie do końca wiesz, albo wiesz za mało
    chyba, że masz zaburzoną motorykę i reakcje są słabe

    Ale chętnie poczytam jeszcze jakiś Twój wywód.
    no proszę, całe 73 strony czekają

    Ps. 30 za rok, jeszcze ciągnę.
    bardzo niebezpiecznie powiem, ale szczerze - do 30 można hulać (żeby mnie nigdy nikt nie zacytował)
    ale potem jak się nie ogarniesz, w przekroju paru lat, które na Ciebie czekają, zaczniesz się powolutku sypać.
    Zaczną się pojawiać dziwne rzeczy, koniec końców kupisz sobie plecak supli z którym się nigdy nie rozstaniesz + do tego namiętne badania krwi i wieczna analiza, taki będzie finał
    correlation doesn't imply causation

  4. #1084
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    tzn, że nie do końca wiesz, albo wiesz za mało
    chyba, że masz zaburzoną motorykę i reakcje są słabe



    no proszę, całe 73 strony czekają



    bardzo niebezpiecznie powiem, ale szczerze - do 30 można hulać (żeby mnie nigdy nikt nie zacytował)
    ale potem jak się nie ogarniesz, w przekroju paru lat, które na Ciebie czekają, zaczniesz się powolutku sypać.
    Zaczną się pojawiać dziwne rzeczy, koniec końców kupisz sobie plecak supli z którym się nigdy nie rozstaniesz + do tego namiętne badania krwi i wieczna analiza, taki będzie finał
    W takim razie otwieram piwo i zabieram się za czytanie, mam całą noc.

  5. #1085
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    Autor: Panda Satchin
    Data premiery: 2020-01-15


    https://bonito.pl/k-1251374-spij-jed...m-okolodobowym

    dużo wygodniej.

    ps.
    jedna nocka Ci nie styknie
    Ostatnio edytowane przez htw ; 30-03-20 o 20:25
    correlation doesn't imply causation

  6. #1086
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    Szef wszystkich szefów, LEPTYNA:

    The leptin activator: New study reveals brain receptor key to burning brown fat

    Some call it baby fat. But recent research has shown that adults have it too—which is a good thing. Brown fat, the so-called good fat that can protect against obesity and associated health risks, like cardiovascular disease and diabetes, is located in small pockets throughout the body. Most mammals use brown fat (and its closely related cousin beige fat) to stay warm.

    "In mice and humans, if you have more brown or beige fat, you are more protected from metabolic disease," says Liangyou Rui, Louis G. D'Alecy Collegiate Professor of Physiology at U-M Medical School, whose lab studies the molecular and physiological mechanisms of obesity, diabetes and fatty liver disease.
    In a new study published in Nature Communications, Rui, first author Lin Jiang, Ph.D. and their colleagues reveal a pathway by which the hormone leptin contributes to weight loss.
    Leptin regulates body weight by controlling appetite and energy expenditure, but exactly how has been a mystery. What is known, says Rui, is that leptin activates brown and beige fat. The new study elucidates a molecular accelerator of leptin action in the brain called Sh2b1.
    His team has found that Sh2b1 in the hypothalamus, an important brain region controlling body temperature and hunger among other functions, promotes the stimulation of the sympathetic nervous system. The sympathetic nervous system sends signals to brown and beige fat to activate it, thus maintaining body weight and metabolism.
    The team demonstrated this proof-of-principle by creating two mouse models. Mice that lacked the Sh2b1 gene in the leptin receptor neurons "had an incredibly reduced sympathetic drive to the brown/beige fat and reduced capability to promote energy expenditure," says Rui.
    This reduced the ability of brown fat to be metabolized into heat, lowering the mice's core body temperature. What's more, the mice also developed obesity, insulin resistance and a fatty liver. In contrast, mice with extra expression of Sh2b1 in their brains were protected from obesity.
    "No one knew that Sh2b1 in the brain controls the sympathetic nervous system or was required for leptin to activate brown fat to increase energy expenditure," notes Rui. As for how this finding could be applied to humans, he says the hope is to eventually find a way to increase expression of Sh2b1 or its ability to enhance leptin signaling and fat burning.
    https://medicalxpress.com/news/2020-...eptor-key.html

    Effects of Low-Energy Diet or Exercise on Cardiovascular Function in Working-Age Adults With Type 2 Diabetes: A Prospective, Randomized, Open-Label, Blinded End Point Trial

    RESULTS
    Eighty-seven participants with T2D (age 51 ± 7 years, HbA1c 7.3 ± 1.1%) and 36 matched control participants were included. At baseline, those with T2D had evidence of diastolic dysfunction (PEDSR 1.01 ± 0.19 vs. 1.10 ± 0.16 s−1, P = 0.02) compared with control participants. Seventy-six participants with T2D completed the trial (30 routine care, 22 exercise, and 24 MRP). The MRP arm lost 13 kg in weight and had improved blood pressure, glycemia, LV mass/volume, and aortic stiffness. The exercise arm had negligible weight loss but increased exercise capacity. PEDSR increased in the exercise arm versus routine care (β = 0.132, P = 0.002) but did not improve with the MRP (β = 0.016, P = 0.731).

    CONCLUSIONS
    In asymptomatic working-age adults with T2D, exercise training improved diastolic function. Despite beneficial effects of weight loss on glycemic control, concentric LV remodeling, and aortic stiffness, a low-energy MRP did not improve diastolic function.
    https://care.diabetesjournals.org/co...3/24/dc20-0129


    A Randomised, Placebo-Controlled, Crossover Study Investigating the Optimal Timing of a Caffeine-Containing Supplement for Exercise Performance

    Conclusion
    In summary, ingestion of a pre-exercise supplement containing 200 mg caffeine 35 min before exercise appeared optimal for improved performance in a subsequent fatiguing time trial, possibly by reducing the perception of effort. Whether this was due to increased circulating paraxanthine requires further investigation.
    https://sportsmedicine-open.springer...0-00246-x#Bib1

    Dietary modifications for enhanced cancer therapy
    correlation doesn't imply causation

  7. #1087
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    Researchers find eating with someone else makes people eat smaller portions, but more often



    A team of researchers at the University of Tokyo has found that people tend to consume smaller amounts of food when they are with someone else than when alone, but eat more often. In their paper published in the journal Royal Society Open Science, the group describes experiments they carried out with volunteer eaters and what they found.
    https://medicalxpress.com/news/2020-...-portions.html

    drzemka poprawia zdolności uczenia się

    A daytime nap restores hippocampal function and improves declarative learning.

    RESULTS:
    A significant Session x Group interaction effect (p<0.001) was observed in which memory was significantly improved in the Nap but not in the Wake group (p<0.001). There was also a Session x Run x Group interaction effect in the left hippocampus (p=0.001), whereby activation during word-pair encoding increased only following the nap. Both performance improvement (rs=0.46, p=0.04) and nap-related increase in hippocampal activation (rs=0.46, p=0.04) were correlated with nap spindle count (12-15 Hz) but not with slow oscillation power (p=0.18).

    CONCLUSIONS:
    After a habitual nocturnal sleep, participants who had a 90-min afternoon nap encoded word pairs better than a comparable group who stayed awake. Increases in hippocampal activation following the nap suggest restored hippocampal function. Naptime spindles may contribute to improved memory.
    https://www.ncbi.nlm.nih.gov/pubmed/32227222

    Contribution of macronutrients to obesity: implications for precision nutrition

    Abstract
    The specific metabolic contribution of consuming different energy-yielding macronutrients (namely, carbohydrates, protein and lipids) to obesity is a matter of active debate. In this Review, we summarize the current research concerning associations between the intake of different macronutrients and weight gain and adiposity. We discuss insights into possible differential mechanistic pathways where macronutrients might act on either appetite or adipogenesis to cause weight gain. We also explore the role of dietary macronutrient distribution on thermogenesis or energy expenditure for weight loss and maintenance. On the basis of the data discussed, we describe a novel way to manage excessive body weight; namely, prescribing personalized diets with different macronutrient compositions according to the individual’s genotype and/or enterotype. In this context, the interplay of macronutrient consumption with obesity incidence involves mechanisms that affect appetite, thermogenesis and metabolism, and the outcomes of these mechanisms are altered by an individual’s genotype and microbiota. Indeed, the interactions of the genetic make-up and/or microbiota features of a person with specific macronutrient intakes or dietary pattern consumption help to explain individualized responses to macronutrients and food patterns, which might represent key factors for comprehensive precision nutrition recommendations and personalized obesity management.
    Key points

    Body weight and adiposity rely on energy equilibrium driven by energy-yielding macronutrient intake and energy expenditure under strict neuroendocrine control.

    Complex energy homeostasis interactions between carbohydrates, lipids and proteins (dietary quantity and quality) follow the interpretation of their separate roles on fuel metabolism.

    The intake of simple sugars and some saturated fatty acids has adverse effects on body adiposity, while protein and fibre consumption seem to beneficially modulate satiety and energy metabolism-related processes.

    Personal genetic background and gut microbiota features contribute to explaining some metabolic inter-individual differences to macronutrient consumption.

    Advances in understanding metabolism pathways and hormonal control depending on macronutrient intake involved in energy utilization are needed for precision and public health nutrition.

    https://www.nature.com/articles/s41574-020-0346-8

    temacie nr 1 w oczekiwaniu na UV

    Historical coronaviruses show evidence of seasonality and immunity

    Using historical data, a UCL research team has found that levels of infection from three common coronaviruses appear to have followed a seasonal pattern in England, with peaks occurring during winter and broadly at the same time as influenza.
    The researchers found that only small amounts of coronavirus were transmitted in the summer.


    https://medicalxpress.com/news/2020-...-immunity.html
    correlation doesn't imply causation

  8. #1088
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    wiecznie niezadowolony\a z własnego ciała ? za mało czasu spędzasz na zewnątrz.
    Nowe badania wykazały, że ogrodnictwo działkowe promuje pozytywny wizerunek ciała

    3 kwietnia 2020
    Gardening helps to grow positive body image

    New research has found that allotment gardening promotes positive body image, which measures someone's appreciation of their own body and its functions, and an acceptance of bodily imperfections.
    The study, published in the journal Ecopsychology and led by Professor Viren Swami of Anglia Ruskin University (ARU), involved 84 gardeners from 12 urban allotment sites in north London.
    https://medicalxpress.com/news/2020-...ody-image.html

    częste stosowanie przypraw może osłabić po posiłkowe pozapalne działanie fast foodów.

    Spices in a High-Saturated-Fat, High-Carbohydrate Meal Reduce Postprandial Proinflammatory Cytokine Secretion in Men with Overweight or Obesity: A 3-Period, Crossover, Randomized Controlled Trial

    Results
    There was a significant spice-by-time interaction on IL-1β (P < 0.001), IL-8 (P = 0.020), and TNF-α (P = 0.009) secretion from LPS-stimulated PBMCs. IL-1β secretion from LPS-stimulated PBMCs was significantly reduced (1314%) at 240 min after HFCM consumption containing 6 g, but not 2 g, of spice blend compared with 0 g spice blend.

    Conclusions
    A HFCM containing 6 g spice blend attenuated HFCM-induced postprandial IL-1β secretion in men with overweight/obesity.
    https://academic.oup.com/jn/advance-...dFrom=fulltext

    dobowa rytmiczności enzymów metabolizujących leki

    Nuclear receptor co-repressor RIP140 regulates diurnal expression of cytochrome P450 2b10 in mouse liver.
    https://www.ncbi.nlm.nih.gov/pubmed/...medium=twitter

    jaka odpowiedź melaniny taki potencjał tworzenia Witaminy D

    Natural sunscreen gene influences how we make vitamin D

    Genetic variations in the skin can create a natural sunscreen, according to University of Queensland researchers investigating the genes linked with vitamin D.
    https://medicalxpress.com/news/2020-...vitamin-d.html

    70 stron na temat cukrzycy i problemów metabolicznych, jaki to ma związek z COVID-19 ?
    Wirus jest bardziej aktywny, gdy poziom glukozy we krwi jest ponad normę. Działa poprzez receptor ACE2. Niebieskie światło z ekranów, lewa fala z mikrofalówek zwiększa poziom glukozy we krwi, (szlak AMPk) czyli pobudza ryzyko infekcji wirusowych.

    COVID-19 Pandemic, Corona Viruses, and Diabetes Mellitus
    https://journals.physiology.org/doi/...ndo.00124.2020

    i oczywiście ma swoją sezonowość,

    Historical coronaviruses show evidence of seasonality and immunity

    Using historical data, a UCL research team has found that levels of infection from three common coronaviruses appear to have followed a seasonal pattern in England, with peaks occurring during winter and broadly at the same time as influenza.
    https://medicalxpress.com/news/2020-...-immunity.html


    niezła myśl
    Ostatnio edytowane przez htw ; 04-04-20 o 14:06
    correlation doesn't imply causation

  9. #1089
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    zapomniałbym - ważna sprawa,
    przez to siedzenie w domu, psychiatrzy oraz specjaliści od żywienia będą mieli pełne ręce roboty

    correlation doesn't imply causation

  10. #1090
    "Using historical data, a UCL research team has found that levels of infection from three common coronaviruses appear to have followed a seasonal pattern in England, with peaks occurring during winter and broadly at the same time as influenza.
    The researchers found that only small amounts of coronavirus were transmitted in the summer. "

    A jak pisalem to na forum to sie smieja i chyba wierzą ze to korona mutant co bedzie cale lato z nami

  11. #1091
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    dane pokazują że lato jest rozwiązaniem, ale nie koniecznie w tym przypadku. Globalny zasięg, ogólna panika, strach, izolacja, ogólne osłabienie, to co się będzie działo latem - suma niespodziewanych czynników współtowarzyszących jest spora - jaka będzie ogólna odpowiedź układu immunologicznego ? trudno powiedzieć.
    Ostatnio edytowane przez htw ; 05-04-20 o 09:46
    correlation doesn't imply causation

  12. #1092
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    dla siedzących przed telefonami całymi dniami, jaki zegar taka podaż kalorii,

    4 April 2020
    Effects of Shift Work on the Eating Behavior of Police Officers on Patrol



    Recent studies indicate that the timing of food intake can significantly affect metabolism and weight management. Workers operating at atypical times of the 24-h day are at risk of disturbed feeding patterns. Given the increased risk of weight gain, obesity and metabolic syndrome in shift working populations, further research is required to understand whether their eating behavior could contribute to these increased metabolic risks. The objective of this study was to characterize the dietary patterns of police officers across different types of shifts in their natural environments. Thirty-one police officers (six women; aged 32.1 ± 5.4 years, mean ± SD) from the province of Quebec, Canada, participated in a 28- to 35-day study, comprising 9- to 12-h morning, evening, and night shifts alternating with rest days. Sleep and work patterns were recorded with actigraphy and diaries. For at least 24 h during each type of work day and rest day, participants logged nutrient intake by timestamped photographs on smartphones. Macronutrient composition and caloric content were estimated by registered dieticians using the Nutrition Data System for Research database. Data were analyzed with linear mixed effects models and circular ANOVA. More calories were consumed relative to individual metabolic requirements on rest days than both evening- and night-shift days (p = 0.001), largely sourced from increased fat (p = 0.004) and carbohydrate (trend, p = 0.064) intake. Regardless, the proportions of calories from carbohydrates, fat, and protein did not differ significantly between days. More calories were consumed during the night, between 2300 h and 0600 h, on night-shift days than any other days (p < 0.001). Caloric intake occurred significantly later for night-shift days (2308 h ± 0114 h, circular mean ± SD) than for rest days (1525 h ± 0029 h; p < 0.01) and was dispersed across a longer eating window (13.9 h ± 3.1 h vs. 11.3 h ± 1.8 h, mean ± SD). As macronutrient proportions were similar and caloric intake was lower, the finding of later meals times on night-shift days versus rest days is consistent with emerging hypotheses that implicate the biological timing of food intake—rather than its quantity or composition—as the differentiating dietary factor in shift worker health
    https://www.mdpi.com/2072-6643/12/4/999

    +

    December 15, 2013
    Glucose: Potential new target for combating annual seasonal flu

    In lab cultures of mammalian cells, researchers showed that influenza A infection could be controlled by targeting viruses' dependence on cellular glucose. Boosting glucose concentrations concomitantly increased influenza infection rate, and treating viral cells with glucose metabolism inhibitor significantly decreased viral replication. Researchers also demonstrated that infection could be restored to high levels simply by adding ATP, major source of energy for cellular reactions, bypassing the need for glucose.
    https://www.sciencedaily.com/release...1215160856.htm

    correlation doesn't imply causation

  13. #1093
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    Dzień Dobry.
    Ja tylko chciałem powiedzieć, że nadal funkcjonuję w czasie "zimowym".
    No ale co mi to szkodzi, rano nigdzie się nie spieszę.
    A może jednak spróbować się przestawić?

  14. #1094
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    Cytat Zamieszczone przez paavo Zobacz posta
    Dzień Dobry.
    a Witam serdecznie, dawno Cię nie było - albo raczej nie obserwuje od dłuższego czasu śladów bytowania.

    Ja tylko chciałem powiedzieć, że nadal funkcjonuję w czasie "zimowym".
    gratuluję, czas solarny, ten normalny jest całkiem spoko więc w jakim celu go przyspieszać ?

    A może jednak spróbować się przestawić?
    eksperymenty z czasem raczej kończą się w 99% (ten 1% zostawiłem z czystej przyzwoitości) katastrofą, w jakim celu zapytam - może masz jakiś ciekawy pomysł ........ ........ ....... ... .?
    Ostatnio edytowane przez htw ; 05-04-20 o 12:30
    correlation doesn't imply causation

  15. #1095
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    Etam, nic poważnego,taki tylko drobiazg.
    Mam mały dysonans poznawczy, zerkam na zegarek a tam o godzinę później niż myślałem.
    No ale da się z tym żyć.

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